Trained Immunity as an Adaptive Branch of Innate Immunity

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F21%3A00550051" target="_blank" >RIV/61388971:_____/21:00550051 - isvavai.cz</a>
Result on the web
<a href="https://www.mdpi.com/1422-0067/22/19/10684" target="_blank" >https://www.mdpi.com/1422-0067/22/19/10684</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/ijms221910684" target="_blank" >10.3390/ijms221910684</a>

Result language
angličtina
Original language name
Trained Immunity as an Adaptive Branch of Innate Immunity
Original language description
The concept of trained immunity has become one of the most interesting and potentially commercially and clinically relevant ideas of current immunology. Trained immunity is realized by the epigenetic reprogramming of non-immunocompetent cells, primarily monocytes/macrophages and natural killer (NK) cells, and is less specific than adaptive immunity, therefore, it may cross-protect against other infectious agents. It remains possible, however, that some of the observed changes are simply caused by increased levels of immune reactions resulting from supplementation with immunomodulators, such as glucan. In addition, the question of whether we can talk about trained immunity in cells with a life span of only few days is still unresolved.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30102 - Immunology

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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