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Rutinosidase and other diglycosidases: Rising stars in biotechnology

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F23%3A00574998" target="_blank" >RIV/61388971:_____/23:00574998 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.sciencedirect.com/science/article/pii/S0734975023001246?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0734975023001246?via%3Dihub</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.biotechadv.2023.108217" target="_blank" >10.1016/j.biotechadv.2023.108217</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Rutinosidase and other diglycosidases: Rising stars in biotechnology

  • Original language description

    Diglycosidases are a special class of glycosidases (EC 3.2.1) that catalyze the separation of intact disaccharide moieties from the aglycone part. The main diglycosidase representatives comprise rutinosidases that cleave rutinose (& alpha,-L-Rha(1-6)-& beta,-D-Glc) from rutin or other rutinosides, and (iso)primeverosidases processing (iso)primeverosides (D-Xyl(1-6)-& beta,-D-Glc), but other activities are known. Notably, some diglycosidases may be ranked as monoglucosidases with enlarged substrate specificity. Diglycosidases are found in various microorganisms and plants. Diglycosidases are used in the food industry for aroma enhancement and flavor modification. Besides their hydrolytic activity, they also possess pronounced synthetic (transglycosylating) capabilities. Recently, they have been demonstrated to glycosylate various substrates in a high yield, including peculiar species like inorganic azide or carboxylic acids, which is a unique feature in biocatalysis. Rhamnose-containing compounds such as rutinose are currently receiving increased attention due to their proven activity in anti-cancer and dermatological experimental studies. This review demonstrates the vast and yet underrated biotechnological potential of diglycosidases from various sources (plant, microbial), and reveals perspectives on the use of these catalysts as well as of their products in biotechnology.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10608 - Biochemistry and molecular biology

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biotechnology Advances

  • ISSN

    0734-9750

  • e-ISSN

    1873-1899

  • Volume of the periodical

    68

  • Issue of the periodical within the volume

    Nov 2023

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    20

  • Pages from-to

    108217

  • UT code for WoS article

    001047405900001

  • EID of the result in the Scopus database

    2-s2.0-85165639949