Strategies for Actinobacteria Isolation, Cultivation, and Metabolite Production that Are Biologically Important
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F25%3A00619380" target="_blank" >RIV/61388971:_____/25:00619380 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22330/25:43931738
Result on the web
<a href="https://pubs.acs.org/doi/10.1021/acsomega.5c01344" target="_blank" >https://pubs.acs.org/doi/10.1021/acsomega.5c01344</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acsomega.5c01344" target="_blank" >10.1021/acsomega.5c01344</a>
Alternative languages
Result language
angličtina
Original language name
Strategies for Actinobacteria Isolation, Cultivation, and Metabolite Production that Are Biologically Important
Original language description
Novel antimicrobial agents are urgently needed to combat antimicrobial resistance from multidrug-resistant organisms. Actinobacteria are key sources of bioactive metabolites with diverse biological activities. Despite their contributions to drug discovery, the process from strain identification to drug manufacturing faces many challenges, especially the rediscovery of known compounds. Recent technological and scientific advancements have accelerated drug development. Efforts to isolate and screen rare actinobacterial species could yield novel bioactive compounds. This review summarizes techniques for selectively isolating rare actinobacteria, improving bioactive metabolite production, and discovering potential strains. Notably, new genomic strategies and new discoveries regarding spectroscopic signature-based bioactive natural products containing specific structural motifs are also discussed. Furthermore, this review updates the compounds derived from rare actinobacteria and their biological applications.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10606 - Microbiology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
ACS Omega
ISSN
2470-1343
e-ISSN
2470-1343
Volume of the periodical
10
Issue of the periodical within the volume
16
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
15923-15934
UT code for WoS article
001470668300001
EID of the result in the Scopus database
2-s2.0-105002771367