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Intravascular ultrasound study of the effect of beta-emitting (Co-55) stents on vascular remodeling and intimal proliferation

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389005%3A_____%2F04%3A00105596" target="_blank" >RIV/61389005:_____/04:00105596 - isvavai.cz</a>

  • Alternative codes found

    RIV/00064203:_____/04:3224

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Intravascular ultrasound study of the effect of beta-emitting (Co-55) stents on vascular remodeling and intimal proliferation

  • Original language description

    The aim of this study was to evaluate vessel remodeling after implantation of high-activity (mean, 41.1 +/- 1.2 muCi) beta-emitting ((CO)-C-55) stents. Proton bombarding in cyclotron has brought the radioactivity. Intravascular ultrasound (IVUS) investigation has been completed in 10 patients. The angiographies performed at 6 months revealed restenosis > 50% in five cases (50%). IVUS analysis demonstrated an absence of remodeling behind the stent, with no changes in total vessel volume (TVV; 353.6 +/- 126.3 and 343.9. +/- 90.6 mm(3)) or plaque + media volume (PMV; 171.7 +/- 57.4 and 166.8 +/- 42.6 mm(3)). On the other hand, lumen volume (LV) within the stent decreased significantly from 181.9 +/- 80.2 to 154.6 +/- 45.2mm(3) (P < 0.02). This was due topresence of neointimal hyperplasia (NIH) at both extremities of implanted stents. No chronic recoil of the implanted stents was found. The analysis of edges (5 mm distally and proximally to the last stent struts) showed no significant ...

  • Czech name

    Intravaskulární echografická studie efektu beta-emitnujícího (55Co) stentu

  • Czech description

    Byla provedena IVUS analýza "edge efektu" po implantaci radioaktivních stentů (majoritní zářič Co-55) zaktivovaných svazkem urychlených protonů z cyklotronu. Efektivní redukce neointimální hyperplasie je patrná v okolí tělesa stentu zatímco na krajích stentu dochází v 66% případů k restenózám díky intimální proliferaci.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    BG - Nuclear, atomic and molecular physics, accelerators

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/KSK4055109" target="_blank" >KSK4055109: Physics, chemistry and informatics for biological, ecological and medicinal applications</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2004

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS

  • ISSN

    1522-1946

  • e-ISSN

  • Volume of the periodical

    61

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    26

  • Pages from-to

    320-325

  • UT code for WoS article

  • EID of the result in the Scopus database