Long-term changes after carotid stenting assessed by intravascular ultrasound and near-infrared spectroscopy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F21%3A10437428" target="_blank" >RIV/00064203:_____/21:10437428 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/21:10437428
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=yJSd1SBTmh" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=yJSd1SBTmh</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.21037/cdt-21-160" target="_blank" >10.21037/cdt-21-160</a>
Alternative languages
Result language
angličtina
Original language name
Long-term changes after carotid stenting assessed by intravascular ultrasound and near-infrared spectroscopy
Original language description
BACKGROUND: Long-term effect of carotid stenting (CAS) on the stabilization of the plaque is almost unrecognized. Vascular healing and remodeling might seal the atherosclerotic plaque with neointimal hyperplasia decreasing the vulnerability. We aimed to assess long-term change in the lipid signal, stent and luminal dimensions and restenosis after CAS with the intravascular ultrasound (IVUS) and near-infrared spectroscopy (NIRS) imaging. METHODS: We performed follow-up angiography and NIRS-IVUS imaging of 58 carotid stents in 52 patients. Median time from CAS to the follow-up examination was 31 months (range, 5-56). The lipid signal of the stented segment was calculated from a NIRS-derived chemogram (a spectroscopic map) as the lipid core burden index (LCBI, a dimensionless number from 0 to 1,000). Planimetric and volumetric measurements from IVUS were performed to assess change in minimal stent area (MSA), minimal luminal area (MLA), stent and luminal volume, late stent expansion and percentage in-stent restenosis (ISR) volume. RESULTS: During the follow-up period, the mean (+-SD) LCBI significantly decreased from 32+-56 to 17+-27 (P=0.002). The mean stent volume significantly increased from 717+-302 to 1,019+-429 mm(3) (P<0.001) with mean stent expansion 43%+-24%. The mean luminal volume increased from 717+-302 to 760+-359 mm(3) (P=0.025) due to ISR encroaching 26%+-15% of the stent volume. CONCLUSIONS: Lipid signal decreased during the follow-up period suggesting stabilization of the plaque. Late stent expansion was balanced with neointimal hyperplasia. TRIAL REGISTRATION: The trial is registered under clinicaltrials.gov NCT03141580.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cardiovascular Diagnosis and Therapy
ISSN
2223-3652
e-ISSN
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Volume of the periodical
11
Issue of the periodical within the volume
6
Country of publishing house
CN - CHINA
Number of pages
10
Pages from-to
1180-1189
UT code for WoS article
000744171400001
EID of the result in the Scopus database
2-s2.0-85123092502