Effect of stenting on the near-infrared spectroscopy-derived lipid core burden index of carotid artery plaque

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F19%3A10394882" target="_blank" >RIV/00064203:_____/19:10394882 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/19:10394882

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=6rW9h-gCNB" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=6rW9h-gCNB</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4244/EIJ-D-17-01054" target="_blank" >10.4244/EIJ-D-17-01054</a>

Result language

angličtina

Original language name

Effect of stenting on the near-infrared spectroscopy-derived lipid core burden index of carotid artery plaque

Original language description

Aims: Catheter-based intravascular near-infrared spectroscopy (NIRS) detects a lipid signal from atherosclerotic plaque. The aim of this study was to describe the effect of carotid artery stenting (CAS) on the lipid signal in a carotid stenosis. Methods and results: We performed NIRS combined with intravascular ultrasound (IVUS) during 120 CAS procedures. Minimal luminal area (MLA) and plaque burden (PB) at the site of MLA were measured with IVUS and lipid core burden index (LCBI), maximal LCBI in a 4 mm segment of the artery (LCBImax) and LCBI in a 4 mm segment at the site of MLA (LCBImla) with NIRS-derived chemograms. NIRS-IVUS imaging was performed at baseline, after stent implantation and after balloon post-dilatation. The most common lesion type was the fibrocalcific plaque (76%). Lipid-rich plaque (LCBImax &gt;= 400) was present in 33% of carotid stenoses and in 20% at the site of MLA. Median MLA increased significantly from baseline to stent implantation (3.63 mm(2) to 5.56 mm(2), p&lt;0.001) and to post-dilatation (5.56 mm(2) to 12.03 mm(2), p&lt;0.001). Median LCBI, LCBImax and LCBImla significantly decreased from baseline to stent implantation: LCBI (60 to 8, p&lt;0.001), LCBImax (294 to 60, p&lt;0.001) and LCBImla (124 to 0, p&lt;0.001). Post-dilatation of the stent had no further significant effect on median LCBI (8 to 5, p=0.890), LCBImax (60 to 50, p=0.690) and LCBImla (0 to 0, p=0.438). Conclusions: Carotid artery stenting significantly reduced the NIRS-derived lipid core burden index at the stented segment.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

EuroIntervention

ISSN

1774-024X

e-ISSN

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Volume of the periodical

15

Issue of the periodical within the volume

3

Country of publishing house

FR - FRANCE

Number of pages

8

Pages from-to

"e289"-"e296"

UT code for WoS article

000471064200014

EID of the result in the Scopus database

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