Biophysical simulation tool PARTRAC: Modelling proton beams at therapy-relevant energies

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389005%3A_____%2F19%3A00523897" target="_blank" >RIV/61389005:_____/19:00523897 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1093/rpd/ncz197" target="_blank" >https://doi.org/10.1093/rpd/ncz197</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/rpd/ncz197" target="_blank" >10.1093/rpd/ncz197</a>

Result language
angličtina
Original language name
Biophysical simulation tool PARTRAC: Modelling proton beams at therapy-relevant energies
Original language description
The biophysical simulation tool PARTRAC has been primarily developed to model radiation physics, chemistry and biology on nanometre to micrometre scales. However, the tool can be applied in simulating radiation effects in an event-by-event manner over macroscopic volumes as well. Benchmark simulations are reported showing that PARTRAC does reproduce the macroscopic Bragg peaks of proton beams, although the penetration depths are underestimated by a few per cent for high-energy beams. PARTRAC also quantifies the increase in DNA damage and its complexity along the beam penetration depth. Enhanced biological effectiveness is predicted in particular within distal Bragg peak parts of therapeutic proton beams.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30224 - Radiology, nuclear medicine and medical imaging

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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