Radiation-induced plasmid DNA damage: effect of concentration and length

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389005%3A_____%2F19%3A00523903" target="_blank" >RIV/61389005:_____/19:00523903 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21340/19:00339326
Result on the web
<a href="https://doi.org/10.1093/rpd/ncz196" target="_blank" >https://doi.org/10.1093/rpd/ncz196</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/rpd/ncz196" target="_blank" >10.1093/rpd/ncz196</a>

Result language
angličtina
Original language name
Radiation-induced plasmid DNA damage: effect of concentration and length
Original language description
Plasmid DNA is commonly used as a simpler substitute for a cell in studies of early effects of ionizing radiation because it allows to determine yields of primary DNA lesions. Experimental studies often employ plasmids of different lengths, in different concentrations in the aqueous solution. Influence of these parameters on the heavy-ion induced yields of primary DNA damage has been studied, using plasmids pUC19 (2686 bp), pBR322 (4361 bp) and pKLAC2 (9107 bp) in 10 and 50 ng/μl concentration. Results demonstrate the impact of plasmid length, while no significant difference was observed between the two concentrations. The uncertainty of the results is discussed.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30224 - Radiology, nuclear medicine and medical imaging

Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)