RADIATION-INDUCED PLASMID DNA DAMAGE: EFFECT OF CONCENTRATION AND LENGTH
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21340%2F19%3A00339326" target="_blank" >RIV/68407700:21340/19:00339326 - isvavai.cz</a>
Alternative codes found
RIV/61389005:_____/19:00523903
Result on the web
<a href="https://doi.org/10.1093/rpd/ncz196" target="_blank" >https://doi.org/10.1093/rpd/ncz196</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/rpd/ncz196" target="_blank" >10.1093/rpd/ncz196</a>
Alternative languages
Result language
angličtina
Original language name
RADIATION-INDUCED PLASMID DNA DAMAGE: EFFECT OF CONCENTRATION AND LENGTH
Original language description
Plasmid DNA is commonly used as a simpler substitute for a cell in studies of early effects of ionizing radiation because it allows to determine yields of primary DNA lesions. Experimental studies often employ plasmids of different lengths, in different concentrations in the aqueous solution. Influence of these parameters on the heavy-ion induced yields of primary DNA damage has been studied, using plasmids pUC19 (2686 bp), pBR322 (4361 bp) and pKLAC2 (9107 bp) in 10 and 50 ng/μl concentration. Results demonstrate the impact of plasmid length, while no significant difference was observed between the two concentrations. The uncertainty of the results is discussed.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10301 - Atomic, molecular and chemical physics (physics of atoms and molecules including collision, interaction with radiation, magnetic resonances, Mössbauer effect)
Result continuities
Project
<a href="/en/project/GJ17-03403Y" target="_blank" >GJ17-03403Y: Links between radiation track structure and clustered DNA damage</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Radiation Protection Dosimetry
ISSN
0144-8420
e-ISSN
1742-3406
Volume of the periodical
186
Issue of the periodical within the volume
2-3
Country of publishing house
GB - UNITED KINGDOM
Number of pages
4
Pages from-to
168-171
UT code for WoS article
000530582200005
EID of the result in the Scopus database
2-s2.0-85082780402