Formation of poly(ethylene glycol) inclusion complexes in aqueous solutions of mixed cyclodextrins.

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F03%3A55033296" target="_blank" >RIV/61389013:_____/03:55033296 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Formation of poly(ethylene glycol) inclusion complexes in aqueous solutions of mixed cyclodextrins.
Original language description
The addition of modified cyclodextrins (modified CDs) accelerates the precipitation in aqueous solutions of poly(ethylene glycol) (PEG) and .alpha.-cyclodextrin (.alpha.-CD), but the final amount of formed solid complex remains unchanged, with no modified CDs detected by MALDI-TOF mass spectrometry. The unsuitability of kinetic turbidity measurements for determination of binding parameters was confirmed. Theoretical calculations based on a model of a chain of freely accessible binding sites demonstratedthat the results do not necessarily contradict the finding that individual modified CD molecules can thread onto PEG chains with the efficiency comparable to that of unmodified .alpha.-CD.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BO - Biophysics
OECD FORD branch
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Project
<a href="/en/project/IAA1050101" target="_blank" >IAA1050101: Biomedically significant complexes between synthetic polymers and natural oligomers</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2003
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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