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Polymer drug carriers for site-specific therapy

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F04%3A00101308" target="_blank" >RIV/61389013:_____/04:00101308 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Polymer drug carriers for site-specific therapy

  • Original language description

    Antibody-targeted doxorubicin-containing classic and star conjugates as well as non-targeted polymer hydrazone conjugates are able completely cure the EL 4 lymphoma-bearing mice in contrast to the free doxorubicin. We showed that during the treatment with polymer-doxorubicin conjugates the immune system of treated mice is activated and effective long-term anti-tumor immunity is established.

  • Czech name

    Polymerní nosiče léčiv pro cílenou terapii

  • Czech description

    Na rozdíl od volného doxorubicinu jsou klasické a hvězdicovité konjugáty směrované protilátkou jakožto i nesměrované hydrazonové konjugáty, vždy obsahující doxorubicin, schopny zcela vyléčit myši nesoucí EL4 lymfom. Ukázali jsme, že během léčby polymerními konjugáty doxorubicinu je imunitní systém myší aktivován a vzniká dlouhodobá protinádorová imunita.

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    CD - Macromolecular chemistry

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2004

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Preprints

  • ISBN

  • ISSN

  • e-ISSN

  • Number of pages

    3

  • Pages from-to

    95-97

  • Publisher name

    State Key Laboratory of Polymer Physics and Chemistry

  • Place of publication

    Peking

  • Event location

    Changchun

  • Event date

    Jun 1, 2004

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article