Reduced UVB-induced corneal damage caused by reactive oxygen and nitrogen species and decreased changes in corneal optics after trehalose treatment

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F10%3A00347608" target="_blank" >RIV/61389013:_____/10:00347608 - isvavai.cz</a>

Alternative codes found

RIV/68378041:_____/10:00347608

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Reduced UVB-induced corneal damage caused by reactive oxygen and nitrogen species and decreased changes in corneal optics after trehalose treatment

Original language description

Trehalose, a nonreducing disaccharide of glucose, is synthetized as a stress responsive factor when cells are exposed to various stress conditions. In UVB-irradiated cornea the effect of trehalose was compared with eyes treated with buffered saline during irradiation. Results show that trehalose significantly reduced oxidative damage of the cornea induced by UVB rays. Trehalose reduced changes of corneal optics, suppressed apoptosis of corneal cells and decreased the formation of peroxynitrite, the reaction product between superoxide and nitric oxide.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FF - ENT (ie. ear, nose, throat), ophthalmology, dentistry

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Histology and Histopathology

ISSN

0213-3911

e-ISSN

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Volume of the periodical

25

Issue of the periodical within the volume

11

Country of publishing house

ES - SPAIN

Number of pages

14

Pages from-to

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UT code for WoS article

000282136800005

EID of the result in the Scopus database

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