Low temperature aqueous living/controlled (RAFT) polymerization of carboxybetaine methacrylamide up to high molecular weights

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F11%3A00360784" target="_blank" >RIV/61389013:_____/11:00360784 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1002/marc.201100176" target="_blank" >http://dx.doi.org/10.1002/marc.201100176</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/marc.201100176" target="_blank" >10.1002/marc.201100176</a>

Result language

angličtina

Original language name

Low temperature aqueous living/controlled (RAFT) polymerization of carboxybetaine methacrylamide up to high molecular weights

Original language description

Poly(carboxybetaine)s (poly(CB)s) are unique, emerging as the only ultra-low fouling materials allowing the preparation of biosensors, fouling resistant nanoparticles, and non-adhesive surfaces for bacteria. Poly(CB)s have been prepared via atom transferradical polymerization, however no control was achieved. Herein, the first successful living/controlled reversible addition fragmentation transfer polymerization of (3-methacryloylamino-propyl)-(2-carboxy-ethyl)-dimethyl-ammonium in acetate buffer (pH 5.2) at 70 and 37?°C is reported. The polymerization afforded very high molecular weight polymers (250?000 g??mol1 in less than 6?h) with low PDI (<1.3) at 70?°C. The polymerization was additionally carried out at 37?°C achieving yet lower PDIs (1.06??PDI??1.15) even at 90% conversion, demonstrating the suitability of the polymerization conditions for bioconjugate grafting. Block copolymerization from biologically relevant poly[HPMA] macroCTAs was additionally performed.

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CD - Macromolecular chemistry

OECD FORD branch

—

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Macromolecular Rapid Communications

ISSN

1022-1336

e-ISSN

—

Volume of the periodical

32

Issue of the periodical within the volume

13

Country of publishing house

DE - GERMANY

Number of pages

8

Pages from-to

958-965

UT code for WoS article

000292547100003

EID of the result in the Scopus database

—