Polymer brushes showing non-fouling in blood plasma challenge the currently accepted design of protein resistant surfaces

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F11%3A00360787" target="_blank" >RIV/61389013:_____/11:00360787 - isvavai.cz</a>

Alternative codes found

RIV/00023736:_____/11:00009263

Result on the web

<a href="http://dx.doi.org/10.1002/marc.201100189" target="_blank" >http://dx.doi.org/10.1002/marc.201100189</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/marc.201100189" target="_blank" >10.1002/marc.201100189</a>

Result language

angličtina

Original language name

Polymer brushes showing non-fouling in blood plasma challenge the currently accepted design of protein resistant surfaces

Original language description

Ultra-low-fouling poly[N-(2-hydroxypropyl) methacrylamide] (poly(HPMA)) brushes have been synthesized for the first time. Similar to the so far only ultra-low-fouling surface, poly(carboxybetaine acrylamide), the level of blood plasma fouling was below the detection limit of surface plasmon resonance (SPR, 0.03 ng??cm2) despite being a hydrogen bond donor and displaying a moderate wettability, thus challenging the currently accepted views for the design of antifouling properties. The antifouling properties were preserved even after two years of storage. To demonstrate the potential of poly(HPMA) brushes for the preparation of bioactive ultra-low fouling surfaces a label-free SPR immunosensor for detection of G Streptococcus was prepared.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CD - Macromolecular chemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Macromolecular Rapid Communications

ISSN

1022-1336

e-ISSN

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Volume of the periodical

32

Issue of the periodical within the volume

13

Country of publishing house

DE - GERMANY

Number of pages

6

Pages from-to

952-957

UT code for WoS article

000292547100002

EID of the result in the Scopus database

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