PEG-modified macroporous poly(glycidyl methacrylate) and poly(2-hydroxyethyl methacrylate) microspheres to reduce non-specific protein adsorption

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F13%3A00391867" target="_blank" >RIV/61389013:_____/13:00391867 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/13:10189371

Result on the web

<a href="http://dx.doi.org/10.1002/mabi.201200446" target="_blank" >http://dx.doi.org/10.1002/mabi.201200446</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/mabi.201200446" target="_blank" >10.1002/mabi.201200446</a>

Result language

angličtina

Original language name

PEG-modified macroporous poly(glycidyl methacrylate) and poly(2-hydroxyethyl methacrylate) microspheres to reduce non-specific protein adsorption

Original language description

To minimize non-specific protein adsorption on macroporous poly(glycidyl methacrylate) and poly(2-hydroxyethyl methacrylate) microspheres containing amino and/or carboxyl groups, the microspheres are coated with ?,?-bis-carboxy poly(ethylene glycol) andamino-terminated poly(ethylene glycol-co-propylene glycol) or ?-methoxy-?-amino poly(ethylene glycol). Adsorption of bovine serum albumin (BSA), ?-globulin, 125I-BSA, pepsin, and chymotrypsin on neat and PEGylated microspheres is determined by UV?VIS spectroscopy of supernatants and eluates or by measurement of radioactivity in an ionization chamber. Neat and PEGylated microspheres adsorb 0.8?70% and 0.02?44% of protein, respectively.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CD - Macromolecular chemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Macromolecular Bioscience

ISSN

1616-5187

e-ISSN

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Volume of the periodical

13

Issue of the periodical within the volume

4

Country of publishing house

DE - GERMANY

Number of pages

9

Pages from-to

503-511

UT code for WoS article

000318043400012

EID of the result in the Scopus database

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