All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

The use of hydrophilic poly(N,N-dimethylacrylamide) for promoting engulfment of magnetic .gamma.-Fe2O3 nanoparticles by mammalian cells

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F13%3A00391930" target="_blank" >RIV/61389013:_____/13:00391930 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1166/jbn.2013.1552" target="_blank" >http://dx.doi.org/10.1166/jbn.2013.1552</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1166/jbn.2013.1552" target="_blank" >10.1166/jbn.2013.1552</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The use of hydrophilic poly(N,N-dimethylacrylamide) for promoting engulfment of magnetic .gamma.-Fe2O3 nanoparticles by mammalian cells

  • Original language description

    Gamma-Fe2O3 nanoparticles obtained by coprecipitation of Fe(II) and Fe(III) chlorides with a base and subsequent oxidation were coated with a shell of hydrophilic biocompatible poly(N,N-dimethylacrylamide) (PDMAAm). Various initiators were attached to the iron oxide surface to enable the use of the ?grafting-from? approach for immobilization of PDMAAm. They included 2,2-azobis(2-methylpropanimidamide) dihydrochloride (AMPA), 2,2-azobis(N-hydroxy-2-methylpropanimidamide) dihydrochloride (ABHA) and 4-cyano-4-{[1-cyano-3-(N-hydroxycarbamoyl)-1-methylpropyl]azo}pentanoic acid (CCHPA). Engulfment of PDMAAm-coated ?-Fe2O3 nanoparticles by murine J774.2 macrophages was investigated. Only some nanoparticles were engulfed by the macrophages. PDMAAm-AMPA-?-Fe2O3and PDMAAm-ABHA-?-Fe2O3 nanoparticles were rapidly engulfed by the cells. In contrast, neat ?-Fe2O3 and PDMAAm-CCHPA-?-Fe2O3 particles induced formation of transparent vacuoles indicating toxicity of the particles. Thus, PDMAAm-coated AM

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CD - Macromolecular chemistry

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Biomedical Nanotechnology

  • ISSN

    1550-7033

  • e-ISSN

  • Volume of the periodical

    9

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    13

  • Pages from-to

    479-491

  • UT code for WoS article

    000316040500019

  • EID of the result in the Scopus database