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Neurotrophin delivery using nanotechnology

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F13%3A00399451" target="_blank" >RIV/61389013:_____/13:00399451 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.drudis.2013.07.010" target="_blank" >http://dx.doi.org/10.1016/j.drudis.2013.07.010</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.drudis.2013.07.010" target="_blank" >10.1016/j.drudis.2013.07.010</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Neurotrophin delivery using nanotechnology

  • Original language description

    Deficits or overexpression of neurotrophins cause neurodegenerative diseases and psychiatric disorders. These proteins are required for the maintenance of the function, plasticity and survival of neurons in the central (CNS) and peripheral nervous systems. Significant efforts have been devoted to developing therapeutic delivery systems that enable control of neurotrophin dosage in the brain. Here, we suggest that nanoparticulate carriers favoring targeted delivery in specific brain areas and minimizingbiodistribution to the systemic circulation should be developed toward clinical benefits of neuroregeneration. We also provide examples of improved targeted neurotrophin delivery to localized areas in the CNS.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CF - Physical chemistry and theoretical chemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GAP208%2F10%2F1600" target="_blank" >GAP208/10/1600: Polymeric particles and nanostructured materials stabilized by surface active molecules</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Drug Discovery Today

  • ISSN

    1359-6446

  • e-ISSN

  • Volume of the periodical

    18

  • Issue of the periodical within the volume

    23-24

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    9

  • Pages from-to

    1263-1271

  • UT code for WoS article

    000328876500017

  • EID of the result in the Scopus database