Neurotrophin delivery using nanotechnology
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F13%3A00399451" target="_blank" >RIV/61389013:_____/13:00399451 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.drudis.2013.07.010" target="_blank" >http://dx.doi.org/10.1016/j.drudis.2013.07.010</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.drudis.2013.07.010" target="_blank" >10.1016/j.drudis.2013.07.010</a>
Alternative languages
Result language
angličtina
Original language name
Neurotrophin delivery using nanotechnology
Original language description
Deficits or overexpression of neurotrophins cause neurodegenerative diseases and psychiatric disorders. These proteins are required for the maintenance of the function, plasticity and survival of neurons in the central (CNS) and peripheral nervous systems. Significant efforts have been devoted to developing therapeutic delivery systems that enable control of neurotrophin dosage in the brain. Here, we suggest that nanoparticulate carriers favoring targeted delivery in specific brain areas and minimizingbiodistribution to the systemic circulation should be developed toward clinical benefits of neuroregeneration. We also provide examples of improved targeted neurotrophin delivery to localized areas in the CNS.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CF - Physical chemistry and theoretical chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GAP208%2F10%2F1600" target="_blank" >GAP208/10/1600: Polymeric particles and nanostructured materials stabilized by surface active molecules</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Drug Discovery Today
ISSN
1359-6446
e-ISSN
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Volume of the periodical
18
Issue of the periodical within the volume
23-24
Country of publishing house
GB - UNITED KINGDOM
Number of pages
9
Pages from-to
1263-1271
UT code for WoS article
000328876500017
EID of the result in the Scopus database
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