Silver-coated monolithic columns for separation in radiopharmaceutical applications

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F14%3A00427359" target="_blank" >RIV/61389013:_____/14:00427359 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1002/jssc.201301325" target="_blank" >http://dx.doi.org/10.1002/jssc.201301325</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/jssc.201301325" target="_blank" >10.1002/jssc.201301325</a>

Result language
angličtina
Original language name
Silver-coated monolithic columns for separation in radiopharmaceutical applications
Original language description
In this study, we demonstrate the preparation of a macroporous monolithic column containing anchored silver nanoparticles and its use for the elimination of excess radioiodine from the radiolabeled pharmaceutical. The poly(glycidyl methacrylate-co-ethylene dimethacrylate) monolith was first functionalized with cystamine and the free thiol groups liberated by reaction with borohydride. In-house-prepared silver nanoparticles were then attached by interaction with the surface thiols. The deiodization process was demonstrated with the commonly used radiopharmaceutical m-iodobenzylguanidine labeled with radionuclide iodine-125.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BO - Biophysics
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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