Blood coagulation and platelet adhesion on polyaniline films
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F15%3A00445122" target="_blank" >RIV/61389013:_____/15:00445122 - isvavai.cz</a>
Alternative codes found
RIV/70883521:28610/15:43873024 RIV/70883521:28150/15:43873024
Result on the web
<a href="http://dx.doi.org/10.1016/j.colsurfb.2015.06.008" target="_blank" >http://dx.doi.org/10.1016/j.colsurfb.2015.06.008</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.colsurfb.2015.06.008" target="_blank" >10.1016/j.colsurfb.2015.06.008</a>
Alternative languages
Result language
angličtina
Original language name
Blood coagulation and platelet adhesion on polyaniline films
Original language description
Polyaniline is a promising conducting polymer with still increasing application potential in biomedicine. Its surface modification can be an efficient way how to introduce desired functional groups and to control its properties while keeping the bulk characteristics of the material unchanged. The purpose of the study was to synthetize thin films of pristine conducting polyaniline hydrochloride, non-conducting polyaniline base and polyaniline modified with poly(2-acrylamido-2-methyl-1-propanesulfonic acid) (PAMPSA) and investigate chosen parameters of their hemocompatibility. The modification was performed either by introduction of PAMPSA during the synthesis or by reprotonation of polyaniline base. The polyaniline hydrochloride and polyaniline base hadno impact on blood coagulation and platelet adhesion. By contrast, the polyaniline reprotonated with PAMPSA completely hindered coagulation thanks to its interaction with coagulation factors Xa, Va and IIa. The significantly lower platel
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CD - Macromolecular chemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Colloids and Surfaces B-Biointerfaces
ISSN
0927-7765
e-ISSN
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Volume of the periodical
133
Issue of the periodical within the volume
1 September
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
8
Pages from-to
278-285
UT code for WoS article
000359172600034
EID of the result in the Scopus database
2-s2.0-84935027104