Silica-modified monodisperse hexagonal lanthanide nanocrystals: synthesis and biological properties

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F15%3A00449390" target="_blank" >RIV/61389013:_____/15:00449390 - isvavai.cz</a>
Alternative codes found
RIV/67985823:_____/15:00449390
Result on the web
<a href="http://dx.doi.org/10.1039/C5NR05572E" target="_blank" >http://dx.doi.org/10.1039/C5NR05572E</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/C5NR05572E" target="_blank" >10.1039/C5NR05572E</a>

Result language
angličtina
Original language name
Silica-modified monodisperse hexagonal lanthanide nanocrystals: synthesis and biological properties
Original language description
Oleic acid-stabilized hexagonal NaYF4:Yb3+/Er3+ nanocrystals, emitting green and red luminescence, were prepared by the high-temperature co-precipitation of lanthanide chlorides. By varying the reaction time and the Ln3+/Na+ ratio, the nanocrystal size can be controlled within the range 16?270 nm. The maximum upconversion quantum yield is achieved under 970 nm excitation. The reverse microemulsion technique using hydrolysis and condensation of tetraethoxysilane is a suitable method to coat the nanocrystal surface with a silica shell to make the particles dispersible and colloidally stable in aqueous media. During the subsequent functionalization, (3-aminopropyl)trimethoxysilane introduced amino groups onto the silica to enable future bioconjugation with the target molecules. All specimens were characterized by TEM microscopy, electron and X-ray diffraction, ATR FT-IR spectroscopy, and upconversion luminescence. Finally, in vitro cytotoxicity and intracellular nanoparticle uptake (using
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CD - Macromolecular chemistry
OECD FORD branch
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Project
<a href="/en/project/GA15-01897S" target="_blank" >GA15-01897S: Magnetic or 90Y-radiolabeled light-upconverting nanoparticles for photodynamic therapy or radiotherapy of tumors</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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