Antifouling fluoropolymer-coated nanomaterials for 19F MRI
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F21%3A00542275" target="_blank" >RIV/61389013:_____/21:00542275 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/21:10438740
Result on the web
<a href="https://pubs.rsc.org/en/content/articlelanding/2021/CC/D1CC00642H#!divAbstract" target="_blank" >https://pubs.rsc.org/en/content/articlelanding/2021/CC/D1CC00642H#!divAbstract</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/D1CC00642H" target="_blank" >10.1039/D1CC00642H</a>
Alternative languages
Result language
angličtina
Original language name
Antifouling fluoropolymer-coated nanomaterials for 19F MRI
Original language description
We developed a multifunctional polymer coating for nanoparticles (NPs) that enables simultaneous detection by 19F MRI and shielding from blood plasma fouling. The coating is based on a water-soluble fluorinated poly(N-(2-fluoroethyl)acrylamide) (PFEAM) that shows high 19F MRI sensitivity, cytocompatibility and excellent antifouling properties, significantly outperforming polyethylene glycol. A proof-of-concept experiment was performed by synthesizing polymer-coated gold NPs that were successfully visualized by 19F MRI at magnetic fields close to the fields used in clinical practice. This universal approach can be used for coating and tracing of various NPs upon suitable polymer chain-end modification.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10403 - Physical chemistry
Result continuities
Project
<a href="/en/project/GA20-07313S" target="_blank" >GA20-07313S: Understanding the "whispers" at interfaces of bioactive polymer brushes</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Chemical Communications
ISSN
1359-7345
e-ISSN
1364-548X
Volume of the periodical
57
Issue of the periodical within the volume
38
Country of publishing house
GB - UNITED KINGDOM
Number of pages
4
Pages from-to
4718-4721
UT code for WoS article
000639824800001
EID of the result in the Scopus database
2-s2.0-85105715257