Catalytic hydrolysis of paraoxon by immobilized copper(II) complexes of 1,4,7-triazacyclononane derivatives
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F24%3A00599510" target="_blank" >RIV/61389013:_____/24:00599510 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/24:10489277
Result on the web
<a href="https://www.mdpi.com/2073-4360/16/20/2911" target="_blank" >https://www.mdpi.com/2073-4360/16/20/2911</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/polym16202911" target="_blank" >10.3390/polym16202911</a>
Alternative languages
Result language
angličtina
Original language name
Catalytic hydrolysis of paraoxon by immobilized copper(II) complexes of 1,4,7-triazacyclononane derivatives
Original language description
Organophosphate neuroactive agents represent severe security threats in various scenarios, including military conflicts, terrorist activities and industrial accidents. Addressing these threats necessitates effective protective measures, with a focus on decontamination strategies. Adsorbents such as bentonite have been explored as a preliminary method for chemical warfare agent immobilization, albeit lacking chemical destruction capabilities. Chemical decontamination, on the other hand, involves converting these agents into non-toxic or less toxic forms. In this study, we investigated the hydrolytic activity of a Cu(II) complex, previously studied for phosphate ester hydrolysis, as a potential agent for chemical warfare decontamination. Specifically, we focused on a ligand featuring a thiophene anchor bound through an aliphatic spacer, which exhibited high hydrolytic activity in its Cu(II) complex form in our previous studies. Paraoxon, an efficient insecticide, was selected as a model substrate for hydrolytic studies due to its structural resemblance to specific chemical warfare agents and due to the presence of a chromogenic 4-nitrophenolate moiety. Our findings clearly show the hydrolytic activity of the studied Cu(II) complexes. Additionally, we demonstrate the immobilization of the studied complex onto a solid substrate of Amberlite XAD4 via copolymerization of its thiophene side group with dithiophene. The hydrolytic activity of the resultant material towards paraoxon was studied, indicating its potential utilization in organophosphate neuroactive agent decontamination under mild conditions and the key importance of surface adsorption of paraoxon on the polymer surface.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10404 - Polymer science
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Polymers
ISSN
2073-4360
e-ISSN
2073-4360
Volume of the periodical
16
Issue of the periodical within the volume
20
Country of publishing house
CH - SWITZERLAND
Number of pages
11
Pages from-to
2911
UT code for WoS article
001341365000001
EID of the result in the Scopus database
2-s2.0-85207653638