Focused tandem shock waves in water and their potential application in cancer treatment
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389021%3A_____%2F11%3A00369995" target="_blank" >RIV/61389021:_____/11:00369995 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Focused tandem shock waves in water and their potential application in cancer treatment
Original language description
Physical principles of novel type of generator of focused tandem shock waves with time delay between the first and second shock waves of 10 ?s have been presented. Generator produces at the focus strong shock wave with peak positive pressure up to 80 MPafollowed by tensile wave with peak negative pressure down up to -80 MPa, generating thus at the focus a large number of cavitation. Biological effects of FTSW were demonstrated in vitro on hemolysis of erythrocytes and cell viability of acute lymphoblastic leukemia cells, and on tumor growth delay experiments ex vivo and in vivo. Synergetic cytotoxicity of FTSW with Photosan on tumor growth was observed, possibly due to cavitation induced sonodynamic effect of FTSW.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
BL - Plasma physics and discharge through gases
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA202%2F09%2F1151" target="_blank" >GA202/09/1151: Focused tandem shock waves and their potential application in cancer treatment and controlled drug delivery</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
Proceedings of 28th International Symposium on Shock Waves
ISBN
978-3-642-25687-5
ISSN
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e-ISSN
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Number of pages
6
Pages from-to
"P"-"2849-P-2849"
Publisher name
Springer Verlag
Place of publication
Manchester
Event location
Manchester
Event date
Jul 17, 2011
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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