Focused tandem shock waves in water and their potential application in cancer treatment

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389021%3A_____%2F12%3A00386673" target="_blank" >RIV/61389021:_____/12:00386673 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/978-3-642-25685-1" target="_blank" >http://dx.doi.org/10.1007/978-3-642-25685-1</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-642-25685-1" target="_blank" >10.1007/978-3-642-25685-1</a>

Result language
angličtina
Original language name
Focused tandem shock waves in water and their potential application in cancer treatment
Original language description
Předneseno na: 28th International Symposium on Shock Waves, Manchester, GB, 17.07.-22.07.2011,str. 839-845: Physical principles of novel type of generator of focused tandem shock waves with time delay between the first and second shock waves of 10 ?s have been presented. Generator produces at the focus strong shock wave with peak positive pressure up to 80 MPa followed by tensile wave with peak negative pressure down up to -80 MPa, generating thus at the focus a large number of cavitation. Biological effects of FTSW were demonstrated in vitro on hemolysis of erythrocytes and cell viability of acute lymphoblastic leukemia cells, and on tumor growth delay experiments ex vivo and in vivo. Synergetic cytotoxicity of FTSW with Photosan on tumor growth was observed, possibly due to cavitation induced sonodynamic effect of FTSW.
Czech name
—
Czech description
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Project
<a href="/en/project/GA202%2F09%2F1151" target="_blank" >GA202/09/1151: Focused tandem shock waves and their potential application in cancer treatment and controlled drug delivery</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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