Synthesis, characterization and in vitro cytotoxicity of Co(II) complexes with N6-substituted adenine derivatives: X-ray structures of 6-(4-chlorobenzylamino)purin-di-ium diperchlorate dihydrate and [Co6(-L6)4Cl8(DMSO)10] ? 4DMSO

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F06%3A00083204" target="_blank" >RIV/61389030:_____/06:00083204 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Synthesis, characterization and in vitro cytotoxicity of Co(II) complexes with N6-substituted adenine derivatives: X-ray structures of 6-(4-chlorobenzylamino)purin-di-ium diperchlorate dihydrate and [Co6(-L6)4Cl8(DMSO)10] ? 4DMSO

Original language description

Cobalt(II) complexes of the composition [Co(L1)Cl(H2O)2] ? H2O (1), [Co(L2)Cl(H2O)2] ? 2H2O (2), [Co(L3)Cl(H2O)2] ? H2O (3), [Co(L4)Cl(H2O)2] ? H2O (4), [Co(L5)Cl(H2O)2] ? H2O (5) and [Co(L6)Cl(H2O)2] ? H2O (6), where HL1 = 6-(3-chlorobenzylamino)purine,HL2 = 6-(4-chlorobenzylamino)purine, HL3 = 6-(2,3-dimethoxybenzylamino)purine, HL4 = 6-(3,4-dimethoxybenzylamino)purine, HL5 = 6-(3-fluorobenzylamino)purine and HL6 = 6-(4-fluorobenzylamino)purine, have been prepared. The compounds have been characterized by elemental analyses, ES+ mass, UV?Vis, IR and NMR spectroscopies, magnetic measurements, molar conductances and thermogravimetric analysis as mononuclear tetrahedral high-spin cobalt(II) complexes. In vitro cytotoxicities of the complexes were tested by a Calcein AM assay against the following human tumour cell lines: malignant melanoma (G361), chronic myelogenous erythroleukemia (K562), osteogenic sarcoma (HOS) and breast adenocarcinoma (MCF7). The molecular structures of 6-(4-c...

Czech name

Synthesis, characterization and in vitro cytotoxicity of Co(II) complexes with N6-substituted adenine derivatives: X-ray structures of 6-(4-chlorobenzylamino)purin-di-ium diperchlorate dihydrate and [Co6(-L6)4Cl8(DMSO)10] ? 4DMSO

Czech description

Synthesis, characterization and in vitro cytotoxicity of Co(II) complexes with N6-substituted adenine derivatives: X-ray structures of 6-(4-chlorobenzylamino)purin-di-ium diperchlorate dihydrate and [Co6(-L6)4Cl8(DMSO)10] ? 4DMSO.

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CA - Inorganic chemistry

OECD FORD branch

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Project

<a href="/en/project/GA203%2F04%2F1168" target="_blank" >GA203/04/1168: Complexes of selected transition metals with cytokinin derivatives: synthesis, characterization and biological activity</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2006

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Polyhedron

ISSN

0277-5387

e-ISSN

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Volume of the periodical

25

Issue of the periodical within the volume

6

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

12

Pages from-to

1421-1432

UT code for WoS article

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EID of the result in the Scopus database

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