All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Genomic imprinting mediates dosage compensation in a young plant XY system

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F18%3A00495629" target="_blank" >RIV/61389030:_____/18:00495629 - isvavai.cz</a>

  • Alternative codes found

    RIV/68081707:_____/18:00495090

  • Result on the web

    <a href="http://dx.doi.org/10.1038/s41477-018-0221-y" target="_blank" >http://dx.doi.org/10.1038/s41477-018-0221-y</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1038/s41477-018-0221-y" target="_blank" >10.1038/s41477-018-0221-y</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Genomic imprinting mediates dosage compensation in a young plant XY system

  • Original language description

    Sex chromosomes have repeatedly evolved from a pair of autosomes. Consequently, X and Y chromosomes initially have similar gene content, but ongoing Y degeneration leads to reduced expression and eventual loss of Y genes(1). The resulting imbalance in gene expression between Y genes and the rest of the genome is expected to reduce male fitness, especially when protein networks have components from both autosomes and sex chromosomes. A diverse set of dosage compensating mechanisms that alleviates these negative effects has been described in animals(2-4). However, the early steps in the evolution of dosage compensation remain unknown, and dosage compensation is poorly understood in plants(5). Here, we describe a dosage compensation mechanism in the evolutionarily young XY sex determination system of the plant Silene latifolia. Genomic imprinting results in higher expression from the maternal X chromosome in both males and females. This compensates for reduced Y expression in males, but results in X overexpression in females and may be detrimental. It could represent a transient early stage in the evolution of dosage compensation. Our finding has striking resemblance to the first stage proposed by Ohno(6) for the evolution of X inactivation in mammals.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10611 - Plant sciences, botany

Result continuities

  • Project

    <a href="/en/project/GA16-08698S" target="_blank" >GA16-08698S: Origin and evolution of sex chromosomes in the dioecious plant Rumex acetosa</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Nature Plants

  • ISSN

    2055-026X

  • e-ISSN

  • Volume of the periodical

    4

  • Issue of the periodical within the volume

    9

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    4

  • Pages from-to

    677-680

  • UT code for WoS article

    000446639100018

  • EID of the result in the Scopus database

    2-s2.0-85052331627