Antifungal activity of the volatiles of Agathosma betulina and Coleonema album commercial essential oil and their effect on the morphology of fungal strains Trichophyton rubrum and T. mentagrophytes

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F19%3A00505481" target="_blank" >RIV/61389030:_____/19:00505481 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15310/19:73596993 RIV/00027006:_____/19:00005389

Result on the web

<a href="http://doi.org/10.1016/j.sajb.2018.03.003" target="_blank" >http://doi.org/10.1016/j.sajb.2018.03.003</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.sajb.2018.03.003" target="_blank" >10.1016/j.sajb.2018.03.003</a>

Result language

angličtina

Original language name

Antifungal activity of the volatiles of Agathosma betulina and Coleonema album commercial essential oil and their effect on the morphology of fungal strains Trichophyton rubrum and T. mentagrophytes

Original language description

The side effects of skin disease antibiotics and lengthy periods of therapy are major shortcomings of both old and newly developed ranges of antifungals. Hence, there is a need to develop an effective, cheap and readily available antifungal of a natural origin to combat skin diseases. The aim of this study was to investigate the effect of Agathosma betulina and Coleonema album essential oil (EO) on the growth and morphology of two fungal strains (Trichophyton rubrum and T. mentagrophytes) responsible for ringworm, and analyse the components of the EO of both plants. There was inhibition/reduction of fungal growth in all plates exposed to EO volatiles. However, the rates of inhibition varied among the fungal species, EO and different volumes tested. The volatiles from A. betulina EO showed a remarkable inhibitory effect with the highest inhibition recorded at 40 μl. The best inhibition was recorded in T. rubrum exposed to volatiles at 40 μl of A. betulina EO with a fungal growth index of 2.3%, indicating its ability of strong fungicidal effects. The mode of action of the EO volatiles was elucidated using electron microscopy. The volatiles inhibited fungal growth by inhibiting the production of spores. Agathosma betulina EO (40 μl) resulted in the destruction of hyphae and spores of T. rubrum. The major components of the EO of A. betulina were limonene (29.8%), menthone (21.6%), and isomenthone (14.7%), while of C. album were pinene (27.4%), and myrcene (14.5%).

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10611 - Plant sciences, botany

Project

<a href="/en/project/LO1204" target="_blank" >LO1204: Sustainable development of research in the Centre of the Region Haná</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

South African Journal of Botany

ISSN

0254-6299

e-ISSN

—

Volume of the periodical

122

Issue of the periodical within the volume

MAY

Country of publishing house

ZA - SOUTH AFRICA

Number of pages

6

Pages from-to

492-497

UT code for WoS article

000469020300032

EID of the result in the Scopus database

2-s2.0-85045857125