The Uptake of Ivermectin and Its Effects in Roots, Leaves and Seeds of Soybean (Glycine max)

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F20%3A00531905" target="_blank" >RIV/61389030:_____/20:00531905 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11160/20:10417259

Result on the web

<a href="http://doi.org/10.3390/molecules25163655" target="_blank" >http://doi.org/10.3390/molecules25163655</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/molecules25163655" target="_blank" >10.3390/molecules25163655</a>

Result language

angličtina

Original language name

The Uptake of Ivermectin and Its Effects in Roots, Leaves and Seeds of Soybean (Glycine max)

Original language description

In recent years interest has grown in the occurrence and the effects of pharmaceuticals in the environment. The aim of this work is to evaluate the risk of fertilizing crops with manure from livestock treated with anthelmintics. The present study was designed to follow the fate of the commonly used anthelmintic drug, ivermectin (IVM) and its metabolites in soybeans (Glycine max (L.) Merr.), a plant that is grown and consumed world-wide for its high content of nutritional and health-beneficial substances. In vitro plantlets and soybean plants, cultivated in a greenhouse, were used for this purpose. Our results showed the uptake of IVM and its translocation to the leaves, but not in the pods and the beans. Four IVM metabolites were detected in the roots, and one in the leaves. IVM exposure decreased slightly the number and weight of the beans and induced changes in the activities of antioxidant enzymes. In addition, the presence of IVM affected the proportion of individual isoflavones and reduced the content of isoflavones aglycones, which might decrease the therapeutic value of soybeans. Fertilization of soybean fields with manure from IVM-treated animals appears to be safe for humans, due to the absence of IVM in beans, the food part of plants. On the other hand, it could negatively affect soybean plants and herbivorous invertebrates.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10609 - Biochemical research methods

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Molecules

ISSN

1420-3049

e-ISSN

—

Volume of the periodical

25

Issue of the periodical within the volume

16

Country of publishing house

CH - SWITZERLAND

Number of pages

10

Pages from-to

3655

UT code for WoS article

000577822200001

EID of the result in the Scopus database

2-s2.0-85089473839