Phytohormone cytokinin guides microtubule dynamics during cell progression from proliferative to differentiated stage
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F20%3A00532829" target="_blank" >RIV/61389030:_____/20:00532829 - isvavai.cz</a>
Result on the web
<a href="http://doi.org/10.15252/embj.2019104238" target="_blank" >http://doi.org/10.15252/embj.2019104238</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.15252/embj.2019104238" target="_blank" >10.15252/embj.2019104238</a>
Alternative languages
Result language
angličtina
Original language name
Phytohormone cytokinin guides microtubule dynamics during cell progression from proliferative to differentiated stage
Original language description
Cell production and differentiation for the acquisition of specific functions are key features of living systems. The dynamic network of cellular microtubules provides the necessary platform to accommodate processes associated with the transition of cells through the individual phases of cytogenesis. Here, we show that the plant hormone cytokinin fine-tunes the activity of the microtubular cytoskeleton during cell differentiation and counteracts microtubular rearrangements driven by the hormone auxin. The endogenous upward gradient of cytokinin activity along the longitudinal growth axis in Arabidopsis thaliana roots correlates with robust rearrangements of the microtubule cytoskeleton in epidermal cells progressing from the proliferative to the differentiation stage. Controlled increases in cytokinin activity result in premature re-organization of the microtubule network from transversal to an oblique disposition in cells prior to their differentiation, whereas attenuated hormone perception delays cytoskeleton conversion into a configuration typical for differentiated cells. Intriguingly, cytokinin can interfere with microtubules also in animal cells, such as leukocytes, suggesting that a cytokinin-sensitive control pathway for the microtubular cytoskeleton may be at least partially conserved between plant and animal cells.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10609 - Biochemical research methods
Result continuities
Project
<a href="/en/project/EF16_019%2F0000738" target="_blank" >EF16_019/0000738: Centre for Experimental Plant Biology</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
EMBO Journal
ISSN
0261-4189
e-ISSN
—
Volume of the periodical
39
Issue of the periodical within the volume
17
Country of publishing house
GB - UNITED KINGDOM
Number of pages
22
Pages from-to
e104238
UT code for WoS article
000548311800001
EID of the result in the Scopus database
2-s2.0-85087860829