Adaptation to Stress: Enhanced Tolerance to Cd2+ and Radiomimetics in Arabidopsis from the Chornobyl Zone
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F25%3A00639823" target="_blank" >RIV/61389030:_____/25:00639823 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.3103/S0095452725050032" target="_blank" >https://doi.org/10.3103/S0095452725050032</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3103/S0095452725050032" target="_blank" >10.3103/S0095452725050032</a>
Alternative languages
Result language
angličtina
Original language name
Adaptation to Stress: Enhanced Tolerance to Cd2+ and Radiomimetics in Arabidopsis from the Chornobyl Zone
Original language description
Investigation of A. thaliana accessions from the Chornobyl zone revealed their increased tolerance to cadmium (Cd2+) and radiomimetics (bleomycin/zeocin). Thus, seedlings of the Chornobyl accession Che07 demonstrated reduced inhibition of root growth under Cd-induced stress. It was observed for the first time that zeocin mainly affects the cells of the root meristem, whereas Cd2+ predominantly affects cells of the elongation zone. This differential response may be due to variations in the stages of cell development, the specificity of genotoxic agents, and the activity of defense mechanisms in different growth zones of the root. Analysis of DNA damage and repair capacity revealed a rapid (within 3 min) activation of repair mechanisms in the Chornobyl A. thaliana accessions Che5 and Che07 after treatment with radiomimetic. Increased expression of the cyclin gene CycB2,1 and decreased expression of the CDKG1 kinase gene after treatment with bleomycin indicate changes in the regulation of the cell cycle, specifically an arrest at the G2 phase. Such an adaptive response likely functions to suppress mitotic entry, which prevents the transfer of damaged DNA to daughter cells. In A. thaliana accessions from the Chornobyl zone, the activation of specific antioxidant enzymes was observed, which counteracts oxidative stress and damage to the genome. It is assumed that A. thaliana from the Chornobyl zone develop unique mechanisms of adaptation to environmental stress and DNA damage, caused by ionizing agents. Investigating the tolerance of plants to ionizing radiation and heavy metals is important for the development of phytoremediation strategies as well as biotechnologies to improve resistance to other abiotic stress factors.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10603 - Genetics and heredity (medical genetics to be 3)
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cytology and Genetics
ISSN
0095-4527
e-ISSN
1934-9440
Volume of the periodical
59
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
495-502
UT code for WoS article
001576338800007
EID of the result in the Scopus database
2-s2.0-105016747410