Circulating Serum MicroRNA-130a as a Novel Putative Marker of Extramedullary Myeloma
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F15%3AA1601FZ8" target="_blank" >RIV/61988987:17110/15:A1601FZ8 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/15:00084098 RIV/00216208:11150/15:10313907 RIV/65269705:_____/15:00063337 RIV/00179906:_____/15:10313907 RIV/00843989:_____/15:E0104827
Result on the web
<a href="http://dx.doi.org/10.1371/journal.pone.0137294" target="_blank" >http://dx.doi.org/10.1371/journal.pone.0137294</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1371/journal.pone.0137294" target="_blank" >10.1371/journal.pone.0137294</a>
Alternative languages
Result language
angličtina
Original language name
Circulating Serum MicroRNA-130a as a Novel Putative Marker of Extramedullary Myeloma
Original language description
Poor outcome of extramedullary disease in multiple myeloma patients and lack of outcome predictors prompt continued search for new markers of the disease. In this report, we show circulating microRNA distinguishing multiple myeloma patients with extramedullary disease from myeloma patients without such manifestation and from healthy donors. MicroRNA-130a was identified by TaqMan Low Density Arrays and verified by quantitative PCR on 144 serum samples (59 multiple myeloma, 55 myeloma with extramedullarydisease, 30 healthy donors) in test and validation cohorts as being down-regulated in myeloma patients with extramedullary disease.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NT14575" target="_blank" >NT14575: Clinical implication of circulating miRNA in monoclonal gammopathies</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
PLOS ONE
ISSN
1932-6203
e-ISSN
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Volume of the periodical
10
Issue of the periodical within the volume
9
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
1-12
UT code for WoS article
000361791000006
EID of the result in the Scopus database
2-s2.0-84946593153