M1/M2 macrophage polarization in human obese adipose tissue
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F18%3AA1901YOV" target="_blank" >RIV/61988987:17110/18:A1901YOV - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.5507/bp.2018.015" target="_blank" >http://dx.doi.org/10.5507/bp.2018.015</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5507/bp.2018.015" target="_blank" >10.5507/bp.2018.015</a>
Alternative languages
Result language
angličtina
Original language name
M1/M2 macrophage polarization in human obese adipose tissue
Original language description
Obesity and insulin resistance are closely associated with chronic inflammation in adipose tissue, where macrophages play an important role. Adipose tissue macrophages can be divided into two main phenotypes: the classical M1 macrophages and alternatively activated macrophages M2. M1 macrophages produce pro-inflammatory cytokines (TNF-alpha, interleukin IL-6 and MCP-1) and thus contribute to the development of insulin resistance. On the other hand, M2 macrophages, anti-inflammatory, are involved in the maintenance of tissue homeostasis and are typical in the adipose tissue of slender individuals. Macrophages can also play a role in the pathogenesis of other serious illnesses such as cardiovascular diseases or cancer. This article reviews the latest data on macrophage polarization in adipose tissue.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30106 - Anatomy and morphology (plant science to be 1.6)
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biomedical Papers-Olomouc
ISSN
1213-8118
e-ISSN
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Volume of the periodical
162
Issue of the periodical within the volume
2
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
4
Pages from-to
79-82
UT code for WoS article
000436347500002
EID of the result in the Scopus database
2-s2.0-85049076955