Diagnostic accuracy of carotid plaque instability by noninvasive imaging: a systematic review and meta-analysis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F24%3AA2503874" target="_blank" >RIV/61988987:17110/24:A2503874 - isvavai.cz</a>
Result on the web
<a href="https://academic.oup.com/ehjcimaging/advance-article/doi/10.1093/ehjci/jeae144/7702685" target="_blank" >https://academic.oup.com/ehjcimaging/advance-article/doi/10.1093/ehjci/jeae144/7702685</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/ehjci/jeae144" target="_blank" >10.1093/ehjci/jeae144</a>
Alternative languages
Result language
angličtina
Original language name
Diagnostic accuracy of carotid plaque instability by noninvasive imaging: a systematic review and meta-analysis
Original language description
Aims There is increasing evidence that plaque instability in the extracranial carotid artery may lead to an increased stroke risk independently of the degree of stenosis. We aimed to determine diagnostic accuracy of vulnerable and stable plaque using noninvasive imaging modalities when compared to histology in patients with symptomatic and asymptomatic carotid atherosclerosis. Methods and results Medline Ovid, Embase, Cochrane Library, and Web of Science were searched for diagnostic accuracy of noninvasive imaging modalities (CT, MRI, US) in the detection of 1) vulnerable/stable plaque, and 2) vulnerable/stable plaque characteristics, compared to histology. The quality of included studies was assessed by QUADAS-2 and univariate and bivariate random-effect meta-analyses were performed. We included 36 vulnerable and 5 stable plaque studies in the meta-analysis, and out of 211 plaque characteristics from remaining studies, we classified 169 as vulnerable and 42 as stable characteristics (28 CT, 120 MRI, 104 US characteristics). We found that MRI had high accuracy [90% (95% CI: 82-95%)] in the detection of vulnerable plaque, similar to CT [86% (95% CI: 76-92%); P > 0.05], whereas US showed less accuracy [80% (95% CI: 75-84%); P = 0.013]. CT showed high diagnostic accuracy in visualizing characteristics of vulnerable or stable plaques (89% and 90%) similar to MRI (86% and 89%; P > 0.05); however, US had lower accuracy (77%, P < 0.001 and 82%, P > 0.05). Conclusion CT and MRI have a similar, high performance in detecting vulnerable carotid plaques, whereas US showed significantly less diagnostic accuracy. Moreover, MRI visualized all vulnerable plaque characteristics allowing for a better stroke risk assessment.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
<a href="/en/project/NU22-04-00389" target="_blank" >NU22-04-00389: Influence of carotid atherosclerotic plaque metabolome on the embolization potential</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
ISSN
2047-2404
e-ISSN
2047-2412
Volume of the periodical
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Issue of the periodical within the volume
10
Country of publishing house
GB - UNITED KINGDOM
Number of pages
11
Pages from-to
1325-1335
UT code for WoS article
001260785000001
EID of the result in the Scopus database
2-s2.0-85206305897