Evolution of Diverse Strategies for Promoter Regulation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17310%2F21%3AA2202A6I" target="_blank" >RIV/61988987:17310/21:A2202A6I - isvavai.cz</a>

Alternative codes found

RIV/68081707:_____/21:00544549

Result on the web

<a href="https://www.sciencedirect.com/science/article/abs/pii/S0168952521000846" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S0168952521000846</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.tig.2021.04.003" target="_blank" >10.1016/j.tig.2021.04.003</a>

Result language

angličtina

Original language name

Evolution of Diverse Strategies for Promoter Regulation

Original language description

DNA is fundamentally important for all cellular organisms due to its role as a store of hereditary genetic information. The precise and accurate regulation of gene transcription depends primarily on promoters, which vary significantly within and between genomes. Some promoters are rich in specific types of bases, while others have more varied, complex sequence characteristics. However, it is not only base sequence but also epigenetic modifications and altered DNA structure that regulate promoter activity. Significantly, many promoters across all organisms contain sequences that can form intrastrand hairpins (cruciforms) or four-stranded structures (G-quadruplex or i-motif). In this review we integrate recent studies on promoter regulation that highlight the importance of DNA structure in the evolutionary adaptation of promoter sequences.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10603 - Genetics and heredity (medical genetics to be 3)

Project

<a href="/en/project/GA18-15548S" target="_blank" >GA18-15548S: Comparative study of DNA interacting properties of the tumor suppressor p53 protein isoforms</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Trends in Genetics

ISSN

0168-9525

e-ISSN

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Volume of the periodical

37

Issue of the periodical within the volume

8

Country of publishing house

GB - UNITED KINGDOM

Number of pages

15

Pages from-to

730-744

UT code for WoS article

000674082400008

EID of the result in the Scopus database

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