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Expression of E-cadherin and c-erbB-2/HER-2/neu Oncoprotein in High-Grade Breast Cancer

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F07%3A00004030" target="_blank" >RIV/61989592:15110/07:00004030 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Expression of E-cadherin and c-erbB-2/HER-2/neu Oncoprotein in High-Grade Breast Cancer

  • Original language description

    E-cadherin (E-CD) is an epithelial-specific cell adhesion molecule, whose expression is lost in invasive lobular (ILC) but not in invasive ductal carcinoma (IDC) of the breast. This cell adhesion system can be disrupted by tyrosine kinase c-erbB-2/HER-2/neu.

  • Czech name

    Exprese E-cadherinu a c-erbB-2/HER-2/neu onkoproteinu v málo diferencovaných karcinomech prsu

  • Czech description

    E-cadherin (E-CD) je pro epitel specifická adhezní molekula, jejíž exprese se, na rozdíl od invazivních duktálních karcinomů, snižuje nebo zcela ztrácí u invazivních lobulárních karcinomů. O tyrozin kináze c-erbB-2/HER-2/neu je známo, že může expresi adhezního systému, jehož součástí je E-CD, narušit.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2007

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Česko-slovenská patologie

  • ISSN

    0009-0611

  • e-ISSN

  • Volume of the periodical

    43

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    6

  • Pages from-to

    87-92

  • UT code for WoS article

  • EID of the result in the Scopus database