Individual differences in the effectiveness of intracoronary bone marrow cell transplantation: the influence of residual perfusion/viability assessed by MIBI SPECT/FDG PET imaging

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F07%3A00004355" target="_blank" >RIV/61989592:15110/07:00004355 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Individual differences in the effectiveness of intracoronary bone marrow cell transplantation: the influence of residual perfusion/viability assessed by MIBI SPECT/FDG PET imaging

Original language description

Aim: We reported that autologous intracoronary mononuclear bone marrow cell (BMC) transplantation improves regional myocardial function of the infarcted wall in a dose-dependent manner (Am Heart J 2006; 152: 975. e9-15.). The aim ofthis study was to analyse perfusion and metabolism in patients with and without the Jeft ventricular (LV) function improvement due to high cell dose transplantation. lVIethods: We included 62 consecutive patients with irreversible damage after the first acute STEM!. Thirty-one paticnts were treated using BMC transplantation, while 31 patients were randomly integrated into a control group. The gated SPECT LV ejection fraction (LVEF) and end-diastolíc/ end-systolic volumes (EDV/ESV) were quantified before BMC therapy and then3 months later. Results: In the control group, the baseIine mean LVEF of 41?9% increased to 44?9% (P=NS); wc observed worsening of EDV/ESV from l54?36 ml/93?32 ml to 167?47 ml/96?4l ml. In the BMC group, LVEFof40?8% increased to 45?9%, an

Czech name

Individuální rozdíly v efektivitě intrakoronární transplantace buněk kostní dřeně: vliv reziduální perfuze/viability zjištěné pomocí MIBI SPECT/FDG PET zobrazení

Czech description

Cíl: V předchozí práci jsme referovali, že při léčbě intrakoronární transplantací buněk kostní dřeně závisí regionální úprava funkce levé komory na dávce podaných buněk (Am Heart J 2006; 152: 975.e9-15.). Cílem této práce byla analýza perfuze a metabolismu u pacientů s a bez úpravy funkce levé komory vlivem transplantace vyšší davky buněk.

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2007

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Nuklearmedizin

ISSN

0029-5566

e-ISSN

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Volume of the periodical

46

Issue of the periodical within the volume

6

Country of publishing house

DE - GERMANY

Number of pages

164

Pages from-to

164

UT code for WoS article

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EID of the result in the Scopus database

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