Individual differences in the effectiveness of intracoronary bone marrow cell transplantation assessed by gated sestamibi SPECT/FDG PET imaging

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F08%3A00007319" target="_blank" >RIV/61989592:15110/08:00007319 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Individual differences in the effectiveness of intracoronary bone marrow cell transplantation assessed by gated sestamibi SPECT/FDG PET imaging

Original language description

Background. The impact of different levels of tracer uptake on improvements of leftventricular (LV) function was analyzed in patients treated by intracoronary bone marrow cell (BMC) transplantation. Methods and Results. Thirty-one patients with irreversible damage after their first acute myocardial infarction (MI), as confirmed by sestamibi single-photon emission computed tomography (MIBI SPECT)/fluorodeoxyglucose positron emission tomography (FDG PET), underwent high-dose (1 108 cells) BMC transplantation, whereas 31 similar patients were randomly integrated into a control group. In 11 BMC-treated patients with very low sestamibi uptake at less than 30% of maximum in the infarcted area, the mean left-ventricular ejection fraction (LVEF) improved after3 months of follow-up by 3% only, and mean end-diastolic/ end-systolic volumes (EDV/ESV) enlarged by 10/1 mL (P NS vs controls). In 20 BMC-treated patients with higher sestamibi uptake in the range of 31% to 50% of maximum, LVEF improved

Czech name

Individuální rozdíly v efektivitě intrakoronární tranplantace buněk kostní dřeně zjištěné vyšetřením gated sestamibi SPECT/FDG PET

Czech description

Úvod: Byl analyzován vliv různé úrovně vychytávání radiofarmaka na zlepšení funkce levé komory u pacientů léčených intrakoronární tranplantace buněk kostní dřeně

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2008

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Nuclear Cardiology

ISSN

1071-3581

e-ISSN

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Volume of the periodical

15

Issue of the periodical within the volume

3

Country of publishing house

US - UNITED STATES

Number of pages

8

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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