Cell Therapy in Patients with Left Ventricular Dysfunction Due to Myocardial Infarction

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F08%3A00006072" target="_blank" >RIV/61989592:15110/08:00006072 - isvavai.cz</a>

Alternative codes found

RIV/65269705:_____/08:#0000355 RIV/00159816:_____/08:#0000429 RIV/00216224:14110/08:00067101

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Cell Therapy in Patients with Left Ventricular Dysfunction Due to Myocardial Infarction

Original language description

Objectives: The purpose of this study was to determine the impact of autologous transplantation of mononuclear bone marrow cells on myocardial function in patients with left ventricular (LV) dysfunction due to an acute myocardial infarction. Methods: Therandomized study included 82 patients with a first acute myocardial infarction treated with a stent implantation. This presentation is a subanalysis of 47 patients with left ventricular dysfunction?EF (ejection fraction) <= 40%. Group H patients (n = 17) received higher number (100,000,000) of cells; Group L patients (n = 13) received lower number (10,000,000) of cells. The patients of control Group C (n = 17) were not treated with cells. The Doppler tissue imaging and single photon emission computed tomography were performed before cell transplantation and 3 months later. Results: At 3 months of follow-up, the baseline EF of 35%, 36%, 35% in Groups H, L, and C increased by 6% (P < 0.01 vs. baseline), 5% (P < 0.01 vs. baseline), and 4%

Czech name

Buněčná terapie u pacientů s dysfunkcí levé komory po infarktu myokardu

Czech description

Cíl: Cílem této práce bylo určit vliv autologní transplantace mononukleárních buněk kostní dřeně na srdeční funkci u pacientů s dysfunkcí levé komory po akutním infarktu myokardu.

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

<a href="/en/project/1A8676" target="_blank" >1A8676: Autologous transplantation of bone marrow cells in patients with acute myocardial infarction. The effect of the number of transplanted cells on the reduction of infarct size</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2008

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Echocardiography

ISSN

0742-2822

e-ISSN

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Volume of the periodical

25

Issue of the periodical within the volume

8

Country of publishing house

US - UNITED STATES

Number of pages

10

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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