A positive correlation between adipocyte fatty acid binding protein and epicardial fat thickness in patients with obstructive sleep apnoea – preliminary data

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F20%3A73602930" target="_blank" >RIV/61989592:15110/20:73602930 - isvavai.cz</a>

Result on the web

<a href="http://www.nel.edu/userfiles/articlesnew/1613324673_41_sova_239-pdf.pdf" target="_blank" >http://www.nel.edu/userfiles/articlesnew/1613324673_41_sova_239-pdf.pdf</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

A positive correlation between adipocyte fatty acid binding protein and epicardial fat thickness in patients with obstructive sleep apnoea – preliminary data

Original language description

BACKGROUND: Obstructive sleep apnoea (OSA) is considered an important risk factor of cardiovascular diseases (CVDs). Epicardial fat (EF) thickness and adipocyte fatty acid-binding protein (A-FABP) may be important links to accelerated atherosclerosis observed in patients with OSA. The aim was to evaluate the relationship between EF thickness and A-FABP levels in patients with OSA. METHODS: 66 patients (of which, 60 were males) of average age 55.6 ± 8.8 years, with newly diagnosed OSA were enrolled in this study. All patients underwent a sleep study, anthropometric parameters were measured, laboratory analysis and echocardiography with EF thickness measurements were collected. Patients were divided into two groups: Group 1: EF &lt; 1mm; Group 2: EF &gt; 1mm. RESULTS: Epicardial fat was present in 51 patients (77.3%). A positive correlation was found between A-FABP levels and % of body fat (r=0.452, p=0.0002). After adjusting to % of body fat, there was no significant difference found in A-FABP levels in the two groups divided. CONCLUSIONS: This study found a positive correlation between serum A-FABP level and % of body fat in patients with moderate to severe obstructive sleep apnoea. No significant difference was found between both groups.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30203 - Respiratory systems

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

NEUROENDOCRINOLOGY LETTERS

ISSN

0172-780X

e-ISSN

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Volume of the periodical

41

Issue of the periodical within the volume

5

Country of publishing house

SE - SWEDEN

Number of pages

6

Pages from-to

239-244

UT code for WoS article

000618092500003

EID of the result in the Scopus database

2-s2.0-85102964213