Whole-genome sequence of a reassortant G9P[4] rotavirus A strain from two children in the Czech Republic

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F20%3A73605717" target="_blank" >RIV/61989592:15110/20:73605717 - isvavai.cz</a>
Alternative codes found
RIV/00027162:_____/20:N0000010
Result on the web
<a href="https://link.springer.com/article/10.1007/s00705-020-04648-w" target="_blank" >https://link.springer.com/article/10.1007/s00705-020-04648-w</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00705-020-04648-w" target="_blank" >10.1007/s00705-020-04648-w</a>

Result language
angličtina
Original language name
Whole-genome sequence of a reassortant G9P[4] rotavirus A strain from two children in the Czech Republic
Original language description
Rotavirus A (RVA) belongs to the family Reoviridae and possesses a trilaminar capsid enclosing 11 segments of double-stranded RNA. RVAs are classified into G and P types based on the nucleotide sequences of the genes coding the capsid proteins VP7 (G-types) and VP4 (P-types) [1]. The whole-genome classification of all 11 genes uses the abbreviations Gx-P[x]-Ix-Rx-Cx-Mx-Ax-Nx-Tx-Ex-Hx, where x indicates the genotype number [2]. Most human RVA strains possess either the Wa-like constellation (I1-R1-C1-M1-A1-N1-T1-E1-H1) or the DS-1-like constellation (I2-R2-C2-M2-A2-N2-T2-E2-H2), which are believed to have evolved from pig and cow RVAs, respectively [3]. G9P[4] RVA strains were first described in Brazil in the 1990s [4], and this genotype later spread to Latin America and the USA [5, 6]. Other strains that were genetically distinct from American G9P[4] RVAs were detected in Japan [7]. G9P[4] strains have become highly prevalent on the Indian subcontinent [8], but they are not very common in Europe. G9P[4] strains have been described in Italy in young patients 0–5 years old and shown to have a complete DS-1-like genome segment constellation [9]. In Finland, G9P[4] strains emerged in the 2015-16 season and have been regularly detected since then [10].
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10606 - Microbiology

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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