Synthesis, spectral, magnetic and in vitro cytotoxic activity studies of cobalt(II) complexes with cytokinin derivates: X-ray structure of 6-(3-methoxybenzylamino)purinium chloride monohydrate

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F05%3A00001885" target="_blank" >RIV/61989592:15310/05:00001885 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Synthesis, spectral, magnetic and in vitro cytotoxic activity studies of cobalt(II) complexes with cytokinin derivates: X-ray structure of 6-(3-methoxybenzylamino)purinium chloride monohydrate

Original language description

Cobalt(II) complexes with 6-(2-hydroxybenzylamino)purine (HL1), 6-(2-methoxybenzylaminopurine (HL2), 6-(3-methoxybenzylamino)purine (HL3) and 6-(4/methoxybenzylamino)purine (HL4) of the composition [Co(L1)Cl(H2O)2].H2O (1), [Co(L2)Cl(H2O)2] (2), [Co(L3)2(H2O)2].2H2O (3), [Co(L4)2(H2O)2].2H2O (4) have been synthesized. The compounds have been characterized by elemental analysis, FT-IR, ES+MS (electrospray mass spectra in the positive ion mode) and electronic spectroscopies, magnetic and conductivity dataas tetrahedral high-spin cobalt(II) complexes. The thermal stability of the complexes has also been studied. The cytotoxicity of the complexes (1-4) was determined by a Calcein acetoxymethyl (AM) assay. Human malignant melanoma (G361), human chronic myelogenous erythroleukemia (K562), human osteogenic sarcoma (HOS) and human breast adenocarcinoma (MCF7) cell lines were used for the testing. The molecular structure of 6-(3-methoxybenzylamino)purinium chloride monohydrate H2L3+.Cl-.H2O i.

Czech name

Příprava, spektrální a magnetické vlastnosti a studium in vitro cytotoxické aktivity kobaltnatých komplexů s cytokininovými deriváty: struktura monohydrátu chloridu 6-(3-methoxybenzylamino)purinia

Czech description

Je popsána příprava, spektrální a magnetické vlastnosti a studium in vitro cytotoxické aktivity kobaltnatých komplexů s cytokininovými deriváty: struktura monohydrátu chloridu 6-(3-methoxybenzylamino)purinia.

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CA - Inorganic chemistry

OECD FORD branch

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Project

<a href="/en/project/GA203%2F04%2F1168" target="_blank" >GA203/04/1168: Complexes of selected transition metals with cytokinin derivatives: synthesis, characterization and biological activity</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2005

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Inorganic Biochemistry

ISSN

0162-0134

e-ISSN

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Volume of the periodical

99

Issue of the periodical within the volume

3

Country of publishing house

US - UNITED STATES

Number of pages

11

Pages from-to

776-786

UT code for WoS article

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EID of the result in the Scopus database

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