Pyrazolo[4,3-D]pyrimidines, processes for their preparation and methods for therapy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F10%3A10212656" target="_blank" >RIV/61989592:15310/10:10212656 - isvavai.cz</a>
Alternative codes found
RIV/61389030:_____/10:00352737
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Pyrazolo[4,3-D]pyrimidines, processes for their preparation and methods for therapy
Original language description
The invention relates to new pyrazolo (4,3-d)pyrimidine derivatives and to their use in suitable utilities, especially diagnostic and therapeutic methods. It is an object of this invention to provide anticancer, anti-inflammatory, antiviral, antineurodegenerative, neurodepressive and immunosuppressive compounds having improved selectivity and efficiency index, i. E. that are less toxic yet more efficacious tha analogues known heretofore. It is an object of this invention to provide 3,5,7-trisubstitutedpyrazolo(4,3-d)pyrimidines, which inhibit the cdks, cell proliferation, and/or induce apoptosis. A further object of the invention is to provide pharmaceutical composition, which comprises a 3,5,7-ftrisubstituted pyrazolo(4,3-d)pyrimidine and a pharmaceutically acceptable carrier.
Czech name
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Czech description
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Classification
Type
P - Patent
CEP classification
CC - Organic chemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Patent/design ID
EP1348707
Publisher
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Publisher name
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Place of publication
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Publication country
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Date of acceptance
Aug 25, 2010
Owner name
Ustav Experimentalni Botaniky AV CR, v.v.i. a Univerzita Palackeho v Olomouci
Method of use
B - Výsledek je využíván orgány státní nebo veřejné správy
Usage type
A - K využití výsledku jiným subjektem je vždy nutné nabytí licence