Sodium azide as a specific quencher of singlet oxygen during chemiluminescent detection by luminol and Cypridina luciferin analogues
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F11%3A33119788" target="_blank" >RIV/61989592:15310/11:33119788 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1002/bio.1296" target="_blank" >http://dx.doi.org/10.1002/bio.1296</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/bio.1296" target="_blank" >10.1002/bio.1296</a>
Alternative languages
Result language
angličtina
Original language name
Sodium azide as a specific quencher of singlet oxygen during chemiluminescent detection by luminol and Cypridina luciferin analogues
Original language description
Reactive oxygen species (ROS) are presently thought to play important role in an increasing number of the physiological and pathological processes in living organisms. Various chemiluminescent (CL) compounds have been studied in order to find suitable and specific probes for the detection of particular ROS species. The CL of luminol is known to be non-specific and can be induced by various oxidants. Two Cypridina luciferin analogues, CLA and MCLA, have been used for the detection of ROS in vivo. CLAs are thought to emit light only when reacting with superoxide and singlet oxygen. It is possible to distinguish the particular ROS by using a specific quencher or scavenger, e.g. superoxide dismutase (SOD) or sodium azide (NaN3). The CL reactions of luminol(3-aminophthalhydrazide), CLA [2-methyl-6-phenyl-3,7-dihydroimidazo(1,2alfa) pyrazin-3-one] and MCLA [2-methyl-6-(p-methoxyphenyl)-3,7-dihydroimidazo(1,2alfa) pyrazin-3-one] were studied in three hydrogen peroxide decomposition systems (
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CF - Physical chemistry and theoretical chemistry
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Luminescence
ISSN
1522-7235
e-ISSN
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Volume of the periodical
26
Issue of the periodical within the volume
6
Country of publishing house
US - UNITED STATES
Number of pages
4
Pages from-to
685-688
UT code for WoS article
000297923800048
EID of the result in the Scopus database
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