Insight into the toxic effects of cis-dichloridoplatinum(II) complexes containing 7-azaindole halogeno derivatives in tumor cells

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F13%3A33147616" target="_blank" >RIV/61989592:15310/13:33147616 - isvavai.cz</a>
Alternative codes found
RIV/68081707:_____/13:00394814
Result on the web
<a href="http://link.springer.com/article/10.1007%2Fs00775-013-1003-7" target="_blank" >http://link.springer.com/article/10.1007%2Fs00775-013-1003-7</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00775-013-1003-7" target="_blank" >10.1007/s00775-013-1003-7</a>

Result language
angličtina
Original language name
Insight into the toxic effects of cis-dichloridoplatinum(II) complexes containing 7-azaindole halogeno derivatives in tumor cells
Original language description
Potential factors which might be involved in the mechanism underlying the cytotoxic effects of the cisplatin analogues cis-[PtCl2(3ClHaza)2] and cis-[PtCl2(3IHaza)2] (3ClHaza and 3IHaza are 3-chloro-7-azaindole and 3-iodo-7-azaindole, respectively) havebeen reported. The results of this work reinforce the idea that direct analogues of conventional cisplatin-containing halogenosubstituted 7-azaindoles offer much promise for the design of novel therapeutic agents.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BO - Biophysics
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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