The induction of lysis in lysogenic strains of Escherichia coli by a new antitumor transplatin derivative and its DNA interactions

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F15%3A33155802" target="_blank" >RIV/61989592:15310/15:33155802 - isvavai.cz</a>
Alternative codes found
RIV/68081707:_____/15:00457631
Result on the web
<a href="http://pubs.rsc.org/en/content/articlepdf/2015/dt/c4dt02603a" target="_blank" >http://pubs.rsc.org/en/content/articlepdf/2015/dt/c4dt02603a</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/C4DT02603A" target="_blank" >10.1039/C4DT02603A</a>

Result language
angličtina
Original language name
The induction of lysis in lysogenic strains of Escherichia coli by a new antitumor transplatin derivative and its DNA interactions
Original language description
The toxicity of the new derivative of transplatin, namely trans-[PtCl2(DEA)(NH3)] (DEA = diethylamine), in which only one NH3 group was replaced by a small, non-bulky DEA ligand, in the cisplatin sensitive and resistant tumor cell lines was examined. The results indicate that this very small modification of the ineffective transplatin molecule results in a considerable enhancement of toxicity in the cancer cells.
Czech name
—
Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BO - Biophysics
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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