A Photoactivatable Platinum(IV) Complex Targeting Genomic DNA and Histone Deacetylases

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F15%3A33156158" target="_blank" >RIV/61989592:15310/15:33156158 - isvavai.cz</a>

Alternative codes found

RIV/68081707:_____/15:00456043

Result on the web

<a href="http://onlinelibrary.wiley.com/wol1/doi/10.1002/anie.201506533/full" target="_blank" >http://onlinelibrary.wiley.com/wol1/doi/10.1002/anie.201506533/full</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/anie.201506533" target="_blank" >10.1002/anie.201506533</a>

Result language

angličtina

Original language name

A Photoactivatable Platinum(IV) Complex Targeting Genomic DNA and Histone Deacetylases

Original language description

Toxic effects of a photoactivatable platinum(IV) complex conjugated with suberoyl-bis-hydroxamic acid in tumor cells have been described. The conjugate exerts, after photoactivation, two functions: activity as both a platinum(II) anticancer drug and histone deacetylase (HDAC) inhibitor in cancer cells.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

BO - Biophysics

OECD FORD branch

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Project

<a href="/en/project/LO1305" target="_blank" >LO1305: Development of the center of advanced technologies and materials</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Angewandte Chemie (International Edition)

ISSN

1433-7851

e-ISSN

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Volume of the periodical

54

Issue of the periodical within the volume

48

Country of publishing house

DE - GERMANY

Number of pages

5

Pages from-to

"14478-14482"

UT code for WoS article

000367724000050

EID of the result in the Scopus database

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