Ultra-Performance Liquid Chromatography/Mass Spectrometry Study of Metabolism of 5-Methylpyranopelargonidin

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F15%3A33156314" target="_blank" >RIV/61989592:15310/15:33156314 - isvavai.cz</a>

Result on the web

<a href="http://link.springer.com/article/10.1007%2Fs10337-014-2832-4" target="_blank" >http://link.springer.com/article/10.1007%2Fs10337-014-2832-4</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10337-014-2832-4" target="_blank" >10.1007/s10337-014-2832-4</a>

Result language

angličtina

Original language name

Ultra-Performance Liquid Chromatography/Mass Spectrometry Study of Metabolism of 5-Methylpyranopelargonidin

Original language description

Anthocyanin dyes represent an important group of plant polyphenols significantly affecting human diet. Their stability in solution is low and it depends on pH, presence of sulfur dioxide and other parameters. Many stable pyranoanthocyanins are formed bycondensation of anthocyanins with small reactive compounds, i.e. pyruvic acid, acetaldehyde, acetone and others, commonly during maturation of food products (e.g. wines and juices). To date, little is known about their metabolism. This communication deals with the study of in vitro metabolism of 5-methylpyranopelargonidin (5-MePPl) as a simple member of the pyranoanthocyanin family and its direct comparison with common flavonoids quercetin and pelargonidin. Human colon adenocarcinoma cells LS174T and human hepatocellular carcinoma cells HepG2 were used for experiments. Metabolites were analyzed by UPLC/MS/MS. Quercetin underwent extensive biotransformation with a metabolic profile typical for flavonoids, corroborating that the used cell

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Chromatographia

ISSN

0009-5893

e-ISSN

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Volume of the periodical

78

Issue of the periodical within the volume

3-4

Country of publishing house

DE - GERMANY

Number of pages

13

Pages from-to

189-201

UT code for WoS article

000348976900005

EID of the result in the Scopus database

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