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Semisynthesis and spectral characterization of 5-methylpyranopelargonidin and 4-methylfuropelargonidin and their separation and detection in strawberry fruit wine

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F17%3A73584095" target="_blank" >RIV/61989592:15310/17:73584095 - isvavai.cz</a>

  • Alternative codes found

    RIV/61388971:_____/17:00479436

  • Result on the web

    <a href="https://www.sciencedirect.com/science/article/pii/S0021967317309196" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0021967317309196</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.chroma.2017.06.051" target="_blank" >10.1016/j.chroma.2017.06.051</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Semisynthesis and spectral characterization of 5-methylpyranopelargonidin and 4-methylfuropelargonidin and their separation and detection in strawberry fruit wine

  • Original language description

    Condensation of anthocyanins and their aglycons with small organic molecules yields more stable natural dyes, e.g. pyranoanthocyanins arising spontaneously in various food products. Reaction of pelargonidin with acetone produces two isomeric anthocyanidin dyes 5-methylpyranopelargonidin and 4-methylfuropelargonidin. A robust semipreparative liquid chromatographic method was developed to isolate both derivatives from a simple aged solution of pelargonidin in methanol: acetone: 37% aqueous hydrochloric acid (1:1:0.008, v/v/v). Detailed interpretation of mass and nuclear magnetic resonance spectra allowed to assign structures of both dyes in isolated fractions. A fast UHPLC-MS method was optimized for the control of their production in the reaction mixture. Use of reversed stationary phase and acidic mobile phases in gradient mode allowed separation of both isomers in less than one minute. Fragmentation of both dyes after collision activated dissociation in collision cell was studied comprehensively and the observed processes were compared with data from quantum calculations (computational chemistry utilizing DFT methods). When comparing both isomers, retro-Diels-Alder fragmentation appears preferred in furo-derivative, while small losses (i.e. methane and water molecules) were more pronounced in pyrano-derivative. Both studied isomeric dyes were found in laboratory prepared strawberry fruit wine and their content was compared with major present anthocyanins and their derivatives.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10406 - Analytical chemistry

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2017

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Chromatography A: Symposium Volumes

  • ISSN

    0021-9673

  • e-ISSN

  • Volume of the periodical

    1510

  • Issue of the periodical within the volume

    aug

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    11

  • Pages from-to

    40-50

  • UT code for WoS article

    000405973400005

  • EID of the result in the Scopus database