PID/WAG-mediated phosphorylation of the Arabidopsis nnnPIN3 auxin transporter mediates polarity switches during gravitropism

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F18%3A73594510" target="_blank" >RIV/61989592:15310/18:73594510 - isvavai.cz</a>

Result on the web

<a href="https://www.nature.com/articles/s41598-018-28188-1" target="_blank" >https://www.nature.com/articles/s41598-018-28188-1</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/s41598-018-28188-1" target="_blank" >10.1038/s41598-018-28188-1</a>

Result language

angličtina

Original language name

PID/WAG-mediated phosphorylation of the Arabidopsis nnnPIN3 auxin transporter mediates polarity switches during gravitropism

Original language description

Intercellular distribution of the plant hormone auxin largely depends on the polar subcellular distribution of the plasma membrane PIN-FORMED (PIN) auxin transporters. PIN polarity switches in response to different developmental and environmental signals have been shown to redirect auxin fluxes mediating certain developmental responses. PIN phosphorylation at different sites and by different kinases is crucial for PIN function. Here we investigate the role of PIN phosphorylation during gravitropic response. Loss-and gain-of-function mutants in PINOID and related kinases but not in D6PK kinase as well as mutations mimicking constitutive dephosphorylated or phosphorylated status of two clusters of predicted phosphorylation sites partially disrupted PIN3 phosphorylation and caused defects in gravitropic bending in roots and hypocotyls. In particular, they impacted PIN3 polarity rearrangements in response to gravity and during feed-back regulation by auxin itself. Thus PIN phosphorylation, besides regulating transport activity and apical-basal targeting, is also important for the rapid polarity switches in response to environmental and endogenous signals.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10608 - Biochemistry and molecular biology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Scientific Reports

ISSN

2045-2322

e-ISSN

—

Volume of the periodical

8

Issue of the periodical within the volume

JUL

Country of publishing house

GB - UNITED KINGDOM

Number of pages

11

Pages from-to

"10279-1"-"10279-11"

UT code for WoS article

000437673200053

EID of the result in the Scopus database

2-s2.0-85049617694