Bacterial resistance to silver nanoparticles

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F19%3A73604007" target="_blank" >RIV/61989592:15310/19:73604007 - isvavai.cz</a>
Result on the web
<a href="https://www.confer.cz/nanocon/2018/135-bacterial-resistance-to-silver-nanoparticles" target="_blank" >https://www.confer.cz/nanocon/2018/135-bacterial-resistance-to-silver-nanoparticles</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Bacterial resistance to silver nanoparticles
Original language description
Silver nanoparticles (NPs) exhibit significant antimicrobial activity against a broad range of bacteria and fungi at concentrations ranging from a few ppm to tens of ppm that are not cytotoxic to human cells. Silver NPs also strongly enhance antibacterial activity against multiresistant, beta-lactamase and carbapenemase-producing Enterobacteriaceae when combined with antibiotics. As a result, silver NPs have already been applied in various biomedical and antimicrobial technologies and products of every-day life as an alternative to conventional antibiotics. While antibiotic resistance has been discussed extensively in the literature, the possible development of resistance to silver NPs after repeated long-term exposure has not been fully explored. We report that bacteria can develop resistance to silver NPs after prolonged exposure. The observed resistance consists in aggregation of silver NPs which consequently eliminates their antibacterial effects. The resistance mechanism can be overcome by preventing the aggregation of silver NPs via their deposition on suitable inorganic substrate such as graphene oxide.
Czech name
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Czech description
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Project
<a href="/en/project/LO1305" target="_blank" >LO1305: Development of the center of advanced technologies and materials</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Proceedings 10th International Conference on Nanomaterials - Research & Application
ISBN
978-80-87294-89-5
ISSN
2694-930X
e-ISSN
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Number of pages
6
Pages from-to
312-317
Publisher name
Tanger infosystems
Place of publication
Ostrava
Event location
Brno
Event date
Oct 17, 2018
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000513131900054

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